新型结核病皮肤测试用于检测潜伏结核病感染
Jinish Doshi1, Kunal Deokar1, Priyanka Gaikwad2
1Department of Pulmonary Medicine, All India Institute of Medical Sciences, Rajkot.
概括
世界卫生组织现在建议基于Mycobacterium结核病抗原的皮肤测试用于潜在结核病诊断. 这增加了现有的方法,如结核素皮肤测试和干扰素γ释放试验,用于潜在的结核病感染.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 诊断 诊断 诊断 诊断
背景情况:
- 潜在结核病感染 (LTBI) 的诊断依赖于特定的测试.
- 基于纯化蛋白衍生物的结核素皮肤测试 (TST) 和干扰素γ释放试验 (IGRA) 是已知的方法.
- 新的诊断建议正在出现.
研究的目的:
- 为了突出世界卫生组织2022年关于LTBI诊断的建议.
- 为了补充当前LTBI诊断工具的审查.
主要方法:
- 审查关于LTBI诊断的现有文献.
- 包括世卫组织对基于Mycobacterium tuberculosis抗原的皮肤测试的有条件建议.
主要成果:
- 世卫组织有条件地建议基于Mycobacterium结核病抗原的皮肤测试用于LTBI诊断.
- 该建议基于证据的确定性非常低.
- 它在诊断领域补充了TST和IGRA.
结论:
- 基于Mycobacterium结核病抗原的皮肤测试是对LTBI诊断的新考虑因素.
- 临床医生应该了解世卫组织最新的指南和证据水平.
- 进一步的研究可能会澄清这些新测试的作用.
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