在中度大动脉狭窄症中,左心室和左心房菌株的增量预后值
Hyun-Jung Lee1, Kyu Kim1, Seo-Yeon Gwak1
1Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
European heart journal. Cardiovascular Imaging
|November 5, 2024
概括
减少左心室全球纵向应变 (LV-GLS) 和左心房储应变 (LARS) 预测中度大动脉狭窄的不良结果. 这些心肌压力测量措施改善了风险分层,用于识别高风险患者.
科学领域:
- 心脏病学 心脏病学
- 心声回声图 (Echocardiography) 是一种心声回声图.
- 心脏机械学 心脏机械学
背景情况:
- 中度大动脉狭窄 (AS) 对具有高风险特征的患者预后不佳.
- 准确的风险分层对于指导中度AS治疗决策至关重要.
研究的目的:
- 在中度AS患者中评估左心室 (LV) 和左心房 (LA) 菌株的增量预后值.
- 确定LV和LA菌株是否可以在传统的临床和心声学变量之外完善风险分层.
主要方法:
- 在923名中度AS患者中,使用斑点追踪回声心脏学测量LV全球纵向应变 (LV-GLS) 和LA储应变 (LARS).
- 分析了心肌应变的绝对值.
- 主要终点是所有原因死亡率和心力衰竭住院治疗的复合结果,平均随访时间为5.9年.
主要成果:
- 减少的LV-GLS和LARS是主要结果的显著独立预测因素.
- 确定了LV-GLS (<17%) 和LARS (<22%) 作为最佳切线.
- 患有减少LV-GLS和LARS的患者表现最差.
- LV-GLS显示出一个比LARS更强的预后值.
结论:
- 降低的LV-GLS和LARS在中度AS中提供增量预后信息.
- 这些菌株参数提高了识别高风险患者的能力,有助于临床决策.
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