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Updated: Jun 17, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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优化HMG-CoA合成酶表达,以通过使用光遗传学进行时间转录调制,在大肠杆菌中增强利蒙生产

Ari Dwijayanti1, Jing Wui Yeoh2,3, Congqiang Zhang4

  • 1CNRS@CREATE, 1 Create Way, #08-01 Create Tower, Singapore 138602, Singapore.

ACS synthetic biology
|November 5, 2024
PubMed
概括

在代谢途径中优化酶表达对于最大限度地提高化合物生产至关重要. 这项研究使用光遗传学来控制大肠杆菌中的HMG-CoA合成酶表达,实现高利蒙产量.

关键词:
在HMGS中,使用的是HMGS.时间转录 时间转录动态控制的动态控制梅瓦诺酸的途径模型配件 模型配件最佳的表达水平最佳的表达水平.视觉遗传学 视觉遗传学

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