盆腔出口的大小作为便失禁的潜在危险因素:基于人口的探索性分析
Brent Hiramoto1,2, Bryn E Falahee2,3, Mayssan Muftah1,2
1Division of Gastroenterology, Hepatology and Endoscopy, Center for Gastrointestinal Motility, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Clinical and translational gastroenterology
|November 5, 2024
概括
较小的骨盆区域与便失禁 (FI) 的风险更高有关. 这一发现表明,骨盆骨结构可能是FI的促成因素,特别是在女性中.
科学领域:
- 盆腔解剖学及其与直肠功能之间的关系.
背景情况:
- 盆骨结构和便失禁 (FI) 之间的关系仍然不太清楚.
- 研究解剖学因素可能会揭示FI病因学的新见解.
研究的目的:
- 检查体重调整的骨盆区域与便失禁的患病率之间的联系.
- 确定骨盆尺寸是否是发展便失禁的危险因素.
主要方法:
- 基于人口的分析,使用来自国家健康和营养检查调查 (2005-2006) 的数据.
- 包括完成了肠道健康调查和双能X射线吸收计 (DXA) 的参与者.
- 对2772名参与者进行了多变量和性别分层分析.
主要成果:
- 盆地区域的最低四分位数与便失禁的几率增加有显著关联.
- 与第三个四分位数相比,最低的骨盆区域四分位数的参与者具有2.05的赔率比 (OR) (CI: 1.18-3.56).
- 在性别分层分析中,特别在女性参与者中观察到类似的关联.
结论:
- 用双能X射线吸收计测量较小的骨盆区域是便失禁的潜在危险因素.
- 骨盆骨结构可能在便失禁的病理生理学中发挥作用,需要进一步调查.
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