基于APTES功能化的氧化物电极的分子印制电化学传感器用于硫法迪亚的测定
Samridhi Chopra1,2, Manisha Balkhandia1,2, Manisha Khatak1,2
1Academy of Scientific and Innovative Research (AcSIR), CSIR-Human Resource Development Centre, (CSIR-HRDC) Campus, Postal Staff College Area, Sector 19, Kamla Nehru Nagar, Ghaziabad, Uttar Pradesh, 201002, India.
Mikrochimica acta
|November 5, 2024
概括
开发了一种新型的电化学传感器,该传感器使用在氧化物 (ITO) 电极上的分子印制聚合物 (MIP) 薄膜,用于敏感的硫黄 (SDZ) 检测. 这种MIP传感器具有很高的选择性和稳定性,可以在牛奶样本中准确量化.
科学领域:
- 电化学 电化学 电化学
- 材料科学 材料科学 材料科学
- 分析化学 分析化学
背景情况:
- 硫法迪亚 (SDZ) 是一种广泛使用的硫胺类抗生素.
- 准确检测SDZ对于食品安全和公共卫生至关重要.
- 现有的检测方法可能缺乏灵敏度,选择性或需要复杂的程序.
研究的目的:
- 开发一种敏感和选择性的电化学传感器,用于检测硫法迪亚.
- 利用分子印记聚合物 (MIP) 技术来提高识别能力.
- 为了验证传感器的性能和适用于真实世界样本,如牛奶.
主要方法:
- 在氧化物 (ITO) 电极上制造分子印制聚合物 (MIP) 薄膜,通过自组装和现场聚合.
- 使用3-aminopropyltriethoxysilane (APTES) 功能化 ITO 电极,以改善聚合物粘附性.
- 删除sulfadiazine模板以在MIP中创建特定的结合点.
- 使用循环电压测量和微分脉冲电压测量进行电化学表征.
主要成果:
- 开发的传感器在0.1至300微米的度范围内表现出对硫法迪亚检测的线性响应.
- 实现了0.11μM的低检测极限.
- 传感器显示出出色的可重复性,可重复性,选择性和稳定性.
- 在添加剂的牛奶样本中成功量化了硫法迪亚,证实了它的实际应用.
结论:
- 基于MIP的电化学传感器提供了一种高度敏感和选择性的硫法迪亚检测方法.
- 传感器的强大性能和在牛奶样本中的适用性突显了其用于常规分析的潜力.
- 这种方法为开发各种分析物的先进电化学传感器提供了一个有希望的平台.
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