使用Lycopersicon esculentum皮肤合成的银纳米颗粒的兼容性和抗菌活性
Esraa Ali1, Samah H Abu-Hussien2, Esraa Hesham1
1New Programs, Faculty of Agriculture, Ain Shams University, PO Box 68, Hadayek Shoubra, Cairo, 11241, Egypt.
AMB Express
|November 5, 2024
概括
使用番茄皮提取物合成了环保的银纳米粒子 (AgNPs). 这些来自Lycopersicon esculentum的AgNP (Le-AgNP) 显示出显著的抗菌和抗真菌活性,具有中度的细胞毒性.
科学领域:
- 绿色化学和纳米技术
- 材料科学与工程 材料科学与工程
背景情况:
- 纳米粒子提供独特的特性作为替代化学控制剂的替代品.
- 对于纳米颗粒的可持续和环保合成方法的需求正在增长.
研究的目的:
- 使用Lycopersicon esculentum (番茄) 皮进行合成银纳米粒子 (AgNPs).
- 描述合成的纳米粒子 (Le-AgNPs) 并评估它们的抗菌,抗真菌和细胞毒性活动.
主要方法:
- 使用番茄皮提取物和酸银的AgNP生物合成.
- 使用紫外可见光谱学,DLS,FTIR,HR-TEM和XRD进行表征.
- 对各种细菌和真菌菌株的抗微生物活性评估.
- 对人类结肠NCM460D正常细胞的细胞毒性评估.
主要成果:
- 紫外线-Vis光谱学证实了310 nm的表面等离子体共振.
- DLS表示颗粒大小为186nm,多分散度指数为0.573.
- HR-TEM揭示了准球形的Le-AgNP,其负泽塔潜力为-68.44mV,表明其高稳定性.
- Le-AgNPs对细菌细菌和大肠杆菌表现出显著的抑制区,以及对Alternaria solani和Candida albicans的中度活性.
- 在NCM460D细胞上观察到IC50为200.53μg/ml的细胞毒性.
结论:
- 番茄皮提取物是一种有效的绿色前体,用于合成稳定的银纳米粒子.
- Le-AgNPs具有有前途的抗菌和抗真菌特性.
- 合成的Le-AgNPs显示出抗微生物疗效和可接受的细胞毒性之间的平衡,用于潜在的应用.
关键词:
莱科佩尔西康 (Lycopersicon esculentum) 是一种的植物.抗微生物活性的抗菌活性.细胞毒性 细胞毒性一半最大的抑制度 (IC50)抑制区直径的抑制区直径.银纳米颗粒 银纳米粒子更多相关视频
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