相关实验视频

Updated: Jun 8, 2025

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

内在免疫调节水凝用于慢性炎症

Yuna Qian^1,2, Jiayi Ding^1,3, Rui Zhao¹

¹National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China. sjl1@wmu.edu.cn.

Chemical Society reviews

|November 5, 2024

概括

内在免疫调节水凝通过积极调节局部免疫微环境,为治疗慢性炎症提供了一种新的方法. 与传统的免疫干预相比,这些先进的材料有望增强组织修复和减少副作用.

科学领域:

生物材料科学生物材料科学
免疫学免疫学免疫学
再生医学是一种再生医学.

背景情况:

慢性炎症是全球主要的健康问题,是导致死亡的主要原因之一.
当前的免疫干预往往导致终身并发症和严重的副作用.
精确控制当地的免疫微环境对于有效的疾病管理至关重要.

研究的目的:

为了回顾慢性炎症的关键元素.
探索内在免疫调节水凝的设计原理.
检查这些水凝在临床转化中的挑战和前景.

主要方法:

关于慢性炎症机制的文献综述.
对内在免疫调节水凝设计策略的分析.
讨论临床前和临床翻译障碍.

主要成果:

内在的免疫调节水凝积极与免疫系统接触.
这些水凝优化免疫相互作用,增强组织修复.
它们提供了一种复杂的策略来管理慢性炎症.

结论:

内在免疫调节水凝是一种有前途的治疗策略.
需要进一步的临床前研究和临床翻译.
这些材料有可能对慢性炎症治疗产生重大影响.

更多相关视频

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

相关概念视频

Inflammatory Response

Inflammatory Response

An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...