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Updated: Jun 8, 2025

Functional Characterization of Endogenously Expressed Human RYR1 Variants
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Published on: June 9, 2021

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稳定的氧化后翻译修饰改变了RyR1的关门特性

Maarten M Steinz1, Nicole Beard2, Emily Shorter1

  • 1Department of Physiology and Pharmacology, Molecular Muscle Physiology and Pathophysiology lab, Karolinska Institutet, Stockholm, Sweden.

The Journal of general physiology
|November 5, 2024
PubMed
概括

稳定的氧化修饰,如3-甲和甲添加物,增加了氨酸受体1型 (RyR1) 开放的概率,影响骨肌肉功能. 这些发现澄清了RyR1在氧化应激条件下的关口.

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