与运动心脏重塑相关的静脉心律不整
Paolo D'Ambrosio1,2,3, Guido Claessen4,5,6, Peter M Kistler1,7,8,9
1Department of Medicine, The University of Melbourne, Grattan St, Parkville, VIC 3010, Australia.
强烈的耐力运动可以通过改变心脏表现型来促进运动员的腹腔失常 (VAs). 需要进一步的研究来了解运动训练,VA和突然心脏病死亡之间的联系.
科学领域:
- 心脏病学 心脏病学
- 运动医学 运动医学
- 运动生理学 运动生理学
背景情况:
- 运动员容易发生心房律乱.
- 强烈的耐力运动,心室节律失常 (VAs) 和心脏突然死亡之间的联系不太清楚.
- "运动员的心脏"可能代表了一种亲心律失常的表型.
研究的目的:
- 审查运动训练和VA之间的联系.
- 讨论潜在的机制,临床意义和运动员体外血管病的管理.
主要方法:
- 审查关于运动诱导VA的现有文献.
- 讨论建议的机制,包括心肌炎症和细胞重塑.
- 分析当前的临床方法和诊断挑战.
主要成果:
- 高强度耐力运动可能会导致心律失常性心脏表型导致VA.
- 动物模型提供有限的见解;人类和大型动物数据很少.
- 仅基于结构性/电气性心脏病来区分VA可能是不够的,如果运动员的心脏是亲节律失常的.
结论:
- 强度运动,心脏重塑和VA之间的关系需要进一步调查.
- 识别有风险的运动员可能需要考虑电生理学特征以及像痕这样的成像标记.
- 需要一个细微的方法来管理运动员的VA,考虑到培训本身的潜在影响.
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