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肥胖对儿童COVID-19疾病严重性的影响
Yakup Çağ1, Ayşe Karaaslan2, Aslı A Çıkrıkçıoğlu1
1Department of Pediatrics, University of Health Sciences, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Türkiye.
肥胖儿童会出现更多的COVID-19症状和肺部感染,这表明疾病的进展更为严重. 这项研究强调肥胖是儿童COVID-19病例的重要风险因素.
科学领域:
- 儿童传染病 儿童传染病
- 公共卫生 公共卫生
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 新冠病毒病2019 (COVID-19) 已导致全球显著的发病率和死亡率.
- 肥胖是严重COVID-19的已知的危险因素,但儿童的机制尚不清楚.
- 了解儿童肥胖对COVID-19严重性的影响对于公共卫生战略至关重要.
研究的目的:
- 调查肥胖和超重状态以及COVID-19在儿科患者的临床过程之间的关联.
- 确定身体质量指数 (BMI) 是否影响COVID-19儿童的症状表现和疾病严重程度.
- 确定与儿科COVID-19肺部感染风险增加相关的潜在BMI值.
主要方法:
- 对116名确诊COVID-19感染的儿科患者 (18岁以下) 的回顾性分析.
- 收集的数据包括人口统计,症状,人体测量 (体重,身高),胸部放射,实验室结果和住院时间.
- 患者根据BMI百分位进行统计比较,分为体重不足,体重正常,超重和肥胖群体.
主要成果:
- 与正常体重和体重不足儿童相比,超重和肥胖儿童的COVID-19症状发生率更高 (p <0.05).
- 肥胖的儿科患者在胸部放射图上显示肺部感染率显著更高 (p < 0.05).
- >91的BMI百分位切线被认为是预测儿科COVID-19病例中的肺部参与的最佳标准.
结论:
- 儿童肥胖与COVID-19感染期间症状频率增加有关.
- 肥胖儿童更容易患上肺部疾病,这表明疾病的发展轨迹更为严重.
- 这些发现强调了管理儿童肥胖的重要性,以减轻与COVID-19相关的风险.
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