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Updated: Jun 8, 2025

Study of Endoplasmic Reticulum and Mitochondria Interactions by In Situ Proximity Ligation Assay in Fixed Cells
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通过细胞表面向的TurboID进行细胞外近位相互作用分析,显示LDLR是结合EGFR的合作伙伴

Rasha Al Mismar1,2, Payman Samavarchi-Tehrani1, Brendon Seale1

  • 1Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health, Toronto, Canada.

Science signaling
|November 5, 2024
PubMed
概括

研究人员开发了细胞外的TurboID (ecTurboID) 来绘制细胞表面的蛋白质相互作用. 这种方法揭示了动态关联,例如EGF刺激导致EGFR和LDLR相互作用,有助于研究血膜蛋白.

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