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Updated: Jun 8, 2025

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells
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Published on: May 30, 2025

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微型和增强的CRISPR激活器用于癌症治疗

Meiyu Huang1, Keshan Wang2, Anshu Li3

  • 1College of Life Sciences, Guangxi Normal University, Guilin, China.

Journal of advanced research
|November 5, 2024
PubMed
概括

研究人员开发了一种新的CRISPR激活 (CRISPRa) 工具,dCas9-NVPR,证明了增强的基因激活和特异性. 这种工具通过恢复瘤抑制基因表达,有效地抑制了癌细胞的增殖,显示了癌症基因治疗的前景.

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