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使用生物发光成像技术可视化骨质细胞中的骨质保护素分泌及其RANKL的抑制

Hotsuna Ninomiya1, Shinji Fukuda2, Hisayo Nishida-Fukuda2

  • 1Department of Orthodontics, School of Dentistry, Aichi Gakuin University, 2-11 Suemori-dori, Chikusa-ku, Nagoya, Aichi 464-8651, Japan; Department of Biochemistry, School of Dentistry, Aichi Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya, Aichi 464-8650, Japan.

Bone
|November 5, 2024
PubMed
概括

核因子卡帕-B连接体 (RANKL) 的受体激活剂抑制了骨质母细胞的骨质保护素 (OPG) 分泌. 这项研究可视化了活细胞中的OPG分泌,揭示了RANKLL.

关键词:
生物发光成像成像技术盖奥西亚 (Gaussia luciferase) 是一种光剂.骨质母细胞是骨质母细胞.骨质保护剂中的骨质保护剂蛋白质分泌 蛋白质分泌兰克尔 (Rankl) 是一个名字.

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