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Updated: Jun 8, 2025

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误解突变对使用in silico分析的人类甲基-CoA合成酶的结构-功能关系的影响

Selma Elabed1, Olfa Alila Fersi1, Abdelaziz Tlili2

  • 1Laboratory of Molecular and Functional Genetics, Faculty of Science University of Sfax, Sfax, Tunisia.

Mitochondrion
|November 5, 2024
PubMed
概括

与甲基氨酸酸尿症相关的苏奇尼尔-CoA合成酶 (SCS) 缺乏症源于有害的基因变异. 这项研究预测了这些突变对SCS蛋白功能的结构和功能影响.

关键词:
停靠对接 停靠对接同性学建模的模拟.没有意义的SNP.结构-功能关系关系结构-功能关系.苏奇尼尔-CoA合成酶是依赖ADP的

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