多囊卵巢形态学,亚临床甲状腺功能低下症和甲状腺刺激激素的切断值,这是一个基于人口的研究
Sima Nazarpour1,2, Maryam Mousavi2, Fahimeh Ramezani Tehrani3,4
1Department of Midwifery, Faculty of Meducal Sciences, Varamin-Pishva Branch, Islamic Azad University, Tehran, Iran.
Reproductive sciences (Thousand Oaks, Calif.)
|November 5, 2024
概括
多囊性卵巢形态 (PCOM) 与患有多囊性卵巢综合征 (PCOS) 的女性的亚临床甲状腺功能低下症 (SCH) 或甲状腺刺激激素 (TSH) 水平没有显著的关联. 这一发现表明PCOM和PCOS患者的甲状腺功能障碍之间没有直接联系.
科学领域:
- 内分泌学 在内分泌学.
- 生殖健康 生殖健康
- 甲状腺疾病 甲状腺疾病
背景情况:
- 多囊卵巢综合征 (PCOS) 经常与甲状腺功能障碍有关.
- 多囊性卵巢形态 (PCOM) 与甲状腺问题,特别是亚临床甲状腺功能低下症 (SCH) 之间的特定关系需要进一步调查.
- 了解这种关联对于全面的PCOS管理至关重要.
研究的目的:
- 在患有PCOS的女性中调查PCOM和SCH之间的关联.
- 为了确定PCOM对甲状腺刺激激素 (TSH) 水平的影响.
- 为了探索与PCOM相关的TSH值.
主要方法:
- 利用了伊朗PCOS患病率研究和胡泽斯坦PCOS患病率研究的数据.
- 将一个PCOM (n=120) 的组与一个对照组 (n=630) 进行比较.
- 采用SCH关联的后勤回归和TSH水平分析的量子力回归,调整年龄,BMI和怀孕.
主要成果:
- 在PCOM和SCH之间没有发现显著的关联 (调整后OR:1.38,95%CI:0.80-2.37;p=0.243).
- 调整后的分析显示,PCOM和对照组之间的TSH水平没有显著差异.
- 在两组中,SCH和TSH值的患病率是可比的.
结论:
- 多囊性卵巢形态 (PCOM) 似乎与患有PCOS的女性的亚临床甲状腺功能低下症 (SCH) 或改变的TSH水平没有显著的关联.
- 这些发现表明,PCOM本身可能不是PCOS患者群体中甲状腺功能障碍的直接风险因素.
- 建议进行进一步的大规模,以人口为基础的研究,并进行详细的甲状腺评估,以证实这些结果.
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