斯特鲁普任务和实践效应在长期COVID和肌痛性脑筋炎/慢性疲劳综合征中显示出认知功能障碍
James N Baraniuk1,2, Kiran Thapaliya3, Maira Inderyas3
1Department of Medicine, Georgetown University, Washington DC, USA. baraniuj@georgetown.edu.
Scientific reports
|November 5, 2024
概括
长期COVID和ME/CFS患者表现出认知功能障碍,其表现在于Stroop任务的反应时间较慢,与健康个体相比. 练习效应没有改善表现,表明持续的认知挑战.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
背景情况:
- 在长期COVID (LC) 和肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS) 中调查认知功能差异.
- 使用Stroop任务来评估这些患者组和健康对照组的认知表现.
研究的目的:
- 为了识别和量化长期COVID和ME/CFS的认知障碍.
- 为了比较LC,ME/CFS和健康个体的认知概况.
主要方法:
- 用一致和不一致的刺激 (颜色单词和中性占位符) 管理Stroop任务.
- 从响应时间到声望刺激和随后的刺激中推断出认知冲突.
- 使用单变量分析和时间过程建模分析了响应时间数据.
主要成果:
- 长期COVID和ME/CFS组的反应时间明显比对照组更长,表明认知功能障碍.
- 初始反应时间在LC中最慢,其次是ME/CFS,然后是对照组,所有组随着时间的推移都呈现出改善.
- 在不一致的声望刺激之后,响应时间较慢,Stroop效应,促进和干扰的模式在不同组之间相似.
结论:
- 长期COVID和ME/CFS的特点是全球反应时间减慢,这表明认知任务期间网络通信受损.
- 在LC和ME/CFS中实践效应有限,表明持续的赤字.
- 对威望刺激效应的分析为认知冲突解决提供了新的见解.
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