通过双盲RCT探索益生菌对成人ADHD管理的影响
Miri Levy Schwartz1, Faiga Magzal2,3, Itamar Yehuda1,4
1Department of Nutritional Sciences, Tel Hai College, 1220800, Upper Galilee, Israel.
Scientific reports
|November 5, 2024
概括
益生菌可以帮助管理注意力缺陷多动症障碍 (ADHD) 的症状. 这项研究发现,益生菌补充剂减少了多动性,并改善了ADHD大学生的学业表现.
科学领域:
- 神经科学是一个神经科学.
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
背景情况:
- 注意缺陷多动性障碍 (ADHD) 是一种流行的神经发育障碍,在成年人中持续存在.
- 肠-大脑轴和微生物群越来越多地与ADHD病理生理学有关.
- 益生菌正在被探索为ADHD的新治疗途径.
研究的目的:
- 为了研究多菌株益生菌补充剂在缓解大学生ADHD症状中的有效性.
- 评估益生菌对学业成绩,胃肠道健康和压力标志物的影响.
主要方法:
- 一个为期3个月的双盲随机对照试验,将多菌株益生菌与被诊断为ADHD的大学生中的安慰剂进行比较.
- 使用MOXO计算机化测试和MATAL问卷进行ADHD症状评估.
- 评估学术记录,生活方式因素,胃肠道症状和指甲皮质醇度 (FCC).
主要成果:
- 益生菌补充剂显著降低了多动性,改善了胃肠道症状.
- 与安慰剂组相比,接受益生菌的参与者表现出更好的学业表现.
- 年龄较小预计总体效益更大;减少FCC与注意力和冲动性改善相关.
结论:
- 多菌株益生菌在治疗ADHD症状,特别是多动症方面表现有前途,并改善学业成绩.
- 益生菌对肠-大脑轴的调节可能会影响ADHD的症状和应激反应.
- 需要进一步的研究来探索特定的益生菌菌株及其对ADHD的临床影响.
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