相关实验视频

Updated: Jun 8, 2025

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

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通过通过KMT2C-H3K4me1/me3表观遗传轴减弱DNA损伤反应,YTHDC1是B细胞急性淋巴细胞白血病的治疗标

Xinxin Li1,2, Minhua Zheng3,4, Shoubao Ma5

  • 1Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University, Xi'an, Shaanxi, PR China.

Leukemia
|November 5, 2024
PubMed
概括

针对YT521-B同源域含蛋白1 (YTHDC1) 的向显示出治疗B细胞急性淋巴细胞白血病 (B-ALL) 的前景. 抑制YTHDC1通过增加B-ALL细胞中的DNA损伤来增强化疗.

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