在社区获得的肺炎患者中,预后营养指数和死亡风险之间的关联:一项回顾性研究
Guangdong Wang1, Na Wang1, Tingting Liu1
1Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shanxi, China.
BMC pulmonary medicine
|November 5, 2024
概括
预后营养指数 (PNI) 与社区获得性肺炎 (CAP) 患者的死亡率降低有关. 较高的PNI水平表明死亡风险降低,这表明PNI水平较低.
科学领域:
- 临床医学 临床医学
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
背景情况:
- 预后营养指数 (PNI) 评估免疫营养状况,并预测各种疾病的结果.
- 在社区获得性肺炎 (CAP) 中PNI的预后价值尚未得到充分确立.
- 这项研究研究了PNI与CAP患者的临床结果之间的关联.
研究的目的:
- 为了评估PNI的预后价值在成人患者中,在ICU入院的CAP患者.
- 确定PNI水平与CAP患者死亡风险之间的关系.
主要方法:
- 使用MIMIC-IV数据库进行回顾性队列研究.
- 1,608名成年CAP患者被分为PNI四分之一.
- 使用了卡普兰-梅尔分析,考克斯回归和受限制立方线 (RCS) 模型.
主要成果:
- 较高的PNI水平与30天和90天死亡率显著降低有关.
- 普尼显示出对死亡率的预测值 (AUC为30天0.71,90天0.68).
- 将PNI与CURB-65结合起来,改善了死亡率的预测.
结论:
- 在CAP患者中,PNI是死亡率的显著负面预测因素.
- 与CURB-65得分相比,PNI对死亡率的预测能力更强.
- PNI可以帮助CAP患者的风险分层.
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