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Updated: Jun 8, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
从出生到年轻成人时期的BMI轨迹与明显的心脏代谢概况有关
Gang Wang1,2,3,4, Dang Wei5, Simon Kebede Merid6
1Division of Internal Medicine, Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China. gang.wang@ki.se.
从出生到成年期持续高体重指数 (BMI) 轨迹与心脏代谢风险增加有关. 然而,儿童BMI升高可能不会损害长期健康,如果它在成年之前解决.
科学领域:
- 心血管疾病的研究研究.
- 人类发育生物学人类发育生物学
- 代谢健康研究研究.
背景情况:
- 现有的关于身体质量指数 (BMI) 轨迹和心血管风险的研究显示出不一致.
- 体重指数测量持续时间和结果评估时间的差异导致了不同的发现.
研究的目的:
- 确定从出生到年轻成年期的身体质量指数 (BMI) 轨迹.
- 分析这些BMI轨迹与心脏代谢风险标志物之间的关联.
主要方法:
- 利用来自瑞典BAMSE出生队列 (n=3204) 的数据进行潜伏类混合建模.
- 分析了从出生到24年随访期间的多个BMI指标 (≥4).
- 评估了与脂质,血压,HbA1c,白细胞和92种与炎症相关的蛋白质的关联.
主要成果:
- 确定了6个BMI轨迹,包括"不断增加的高"和"高度加速的增加"组.
- 这些高BMI轨迹的群体表现出较高的总胆固醇,甘油三,LDL,HbA1c和炎症标志物.
- "日益加快缓解"的BMI组没有增加心脏代谢风险标志物.
结论:
- 持续高或快速增长的BMI轨迹与年轻成人心脏代谢风险标志物升高有关.
- 如果儿童的BMI升高没有持续到成年时,它可能不会有害.
- 纵向的BMI模式对于了解长期心血管健康至关重要.
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