在白风中同时存在的自身免疫和自身炎症疾病的患病率:来自埃及的基于调查的研究
Samar Tharwat1,2, Fatma Hamdy3, Sara Hamdy4
1Rheumatology & Immunology Unit, Department of Internal Medicine, Faculty of Medicine, Mansoura University Hospital, El Gomhouria St, Mansoura, Dakahlia Governorate, 35511, Egypt. samartharwat2000@mans.edu.eg.
BMC rheumatology
|November 6, 2024
概括
自身免疫和自身炎症性疾病 (AIIDs) 影响近27%的白风患者. 年龄,女性性别和AIID家族史是白风中这些共存条件的关键预测因素.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 遗传学 是一个遗传学.
背景情况:
- 白风的确切病因仍然难以捉摸,提出的促成因素包括遗传学,黑色素细胞破坏,自身免疫力和氧化应激.
- Vitiligo 病原体是多因素的,涉及遗传倾向和环境触发因素之间的复杂相互作用.
研究的目的:
- 确定在埃及白风患者中共存的自身免疫和自身炎症性疾病 (AIID) 的患病率.
- 确定与白风患者中AIIDs存在相关的风险因素.
主要方法:
- 对埃及白风患者及其家长进行了基于网络的调查,收集了人口统计,临床和治疗数据.
- 评估了白风病活动 (VIDA) 评分,参与者报告了任何同时存在的AIID.
主要成果:
- 在294名参与者中,27%的人报告至少有一次AIID. 最常见的AIID是自身免疫性甲状腺疾病 (16%),白发性脱发 (4.8%),牛皮和类风湿性关节炎 (3.7%).
- 统一分析表明,年龄较大,女性性别,疾病持续时间较长,白风影响的身体表面积较大,以及AIID家族史是AIID存在的重要预测因素.
结论:
- 自身免疫和自身炎症性疾病是白风患者常见的并发症.
- 年龄,女性性别和AIID家族史是白风患者AIID发展的重要预测因素.
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