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Updated: Jun 8, 2025

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工程自调节巨细胞用于向的抗炎药物输送

Molly Klimak1,2,3,4, Amanda Cimino1,2,3,4, Kristin L Lenz1,3,4

  • 1Department of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, MO, 63110, USA.

Arthritis research & therapy
|November 6, 2024
PubMed
概括

工程化巨细胞提供IL-1受体对抗剂 (IL-1Ra) 来对抗类风湿性关节炎 (RA) 炎症. 这些"智能"细胞向炎症关节,在临床前模型中减少疾病的严重程度.

关键词:
细胞疗法是一种细胞疗法.设计者细胞设计者细胞类风湿性关节炎 类风湿性关节炎 类风湿性关节炎合成生物学 合成生物学

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Inflammatory Response01:28

Inflammatory Response

An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
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