美国的痛风爆发负担:多年横截面调查研究
Jasvinder A Singh1,2,3, Amy Morlock4, Robert Morlock4
1Medicine Service, Michael E. DeBakey VA Medical Center, Houston, Texas.
痛风发作在美国成年人中很常见,而且报告不足,近72%的人没有告诉医生. 这凸显了除了临床文档之外,需要捕捉全患者的痛风负担.
科学领域:
- 类风湿病学 类风湿病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 痛风是一种常见的炎症性关节炎,其特点是反复爆发.
- 准确评估痛风爆发负担对于患者管理和医疗保健资源分配至关重要.
研究的目的:
- 为了评估美国成年人中痛风爆发的负担.
- 检查与痛风爆发相关的患者特征.
- 评估与痛风爆发相关的结果.
主要方法:
- 美国18岁及以上的成年人使用随机分层抽样框架进行了在线调查.
- 患有痛风的参与者提供了关于治疗,血清尿酸盐水平,发作频率和对疾病控制的满意度的数据.
- 经过验证的仪器评估了健康状况,焦虑和抑郁;多变量逻辑回归确定了预测爆发报告的因素.
主要成果:
- 包括933名患有痛风的参与者;与对照人群相比,他们年龄较大,更有可能是男性,白人和已婚.
- 平均每人每年的痛风爆发负担为6.6次.
- 大约72%的痛风爆发没有向医生报告,预先治疗或预防.
结论:
- 痛风发作是美国成年人痛风的重大负担.
- 患者报告不足的痛风爆发的比例很大.
- 仅仅依靠医生记录的发作,低估了痛风对患者的真正影响.
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