能量调整的炎症饮食指数和发生抑郁症之间的关联:一个队列研究
Yinghong Zhai1, Fangyuan Hu2,3, Lei Yuan4
1Clinical Research Unit, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai200011, People's Republic of China.
The British journal of nutrition
|November 6, 2024
概括
通过能量调整的饮食炎症指数 (E-DII) 衡量的促炎症饮食与抑郁症的风险增加有关. 这一发现强调了饮食和心理健康之间的联系,表明饮食变化可能会影响抑郁风险.
科学领域:
- 营养流行病学 营养流行病学
- 精神病学流行病学 精神病学流行病学
- 公共卫生 公共卫生
背景情况:
- 饮食显著影响健康,新出现的证据将饮食模式与心理健康联系起来.
- 饮食和抑郁风险之间的关系需要使用可靠的方法和大型数据集进行进一步调查.
研究的目的:
- 调查能量调整的饮食炎症指数 (E-DII) 和发生抑郁症之间的关联.
- 分析这个关联在英国生物库的大群体内,控制各种混因素.
主要方法:
- 利用了来自152,853名英国生物库参与者的数据.
- 使用27个食品参数计算了E-DII,并使用倾向性得分匹配来减少偏差.
- 进行了单变量,多变量逻辑回归,灵敏度和子组分析,调整了社会人口统计学,生活方式和慢性疾病.
主要成果:
- 在较高的E-DII得分和抑郁症增加的可能性 (OR = 1.12) 之间观察到显著的正相关性.
- 倾向性得分匹配证实了这一关联,较高的E-DII与发生抑郁症有关.
- 在排除2型糖尿病或高血压患者和敏感性分析后,研究结果保持一致.
结论:
- 摄入具有较高的促炎潜力的饮食与患抑郁症的风险增加有关.
- 饮食中的炎症可能是影响未来抑郁风险的可改变因素.
- 对预防抑郁症的饮食干预措施进行进一步的研究是有必要的.
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