计算机辅助药物发现表观遗传调节器在多因子疾病的双目标治疗中

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Updated: Jun 8, 2025

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Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

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Slavica Oljacic1, Marija Popovic Nikolic1, Brankica Filipic2

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11000 Belgrade, Serbia.

Current topics in medicinal chemistry
|November 6, 2024
PubMed
概括

双位抑制剂通过同时向遗传和表观遗传因素,为治疗癌症和神经退行提供了新的希望. 计算机辅助药物设计有助于开发复杂疾病的这些新疗法.

关键词:
计算机辅助药物设计 (CADD).

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