用对比增强的超声波来诊断具有不确定细胞学的甲状腺结节:一项回顾性研究
Yingchun Liu1, Hui Liu1,2, Jia Zhan1
1Department of Ultrasound, Huadong Hospital, Fudan University, Shanghai, China.
Clinical endocrinology
|November 6, 2024
概括
与对比度增强的超声波 (CEUS) 有助于诊断甲状腺结节的不确定的细胞学. 将CEUS与常规超声波 (CUS) 结合起来,可显著提高恶性瘤预测的准确性.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 带有不确定的细胞学的甲状腺结节带来了诊断挑战.
- 传统的超声波引导细针吸收活检有其局限性.
- 与对比度增强的超声波 (CEUS) 为甲状腺结节提供了高的诊断性能.
研究的目的:
- 评估CEUS对甲状腺结节的诊断价值,其细胞学不确定.
- 为了比较CEUS,CUS及其组合的诊断性能.
主要方法:
- 一项涉及116个甲状腺结节的研究,细胞学不明.
- 传统的超声波 (CUS) 和CEUS,其次是细针吸收活检.
- 后勤回归分析以确定恶性瘤的独立风险因素.
- 接收器操作特征 (ROC) 曲线分析以比较诊断准确性.
主要成果:
- CEUS显示出高的诊断性能 (AUC=0.848).
- 恶性瘤的独立风险因素包括高于宽的形状,不规则的边缘,微化,低增强,异质性和特定的洗进/洗出模式.
- 结合CUS和CEUS实现了最高的诊断准确性 (AUC=0.934),显著优于单独使用任何一种模式.
结论:
- CEUS是诊断甲状腺结节不确定的细胞学的一个有价值的工具.
- 在这些具有挑战性的病例中,CUS和CEUS的联合使用在预测恶性瘤方面提供了卓越的准确性.
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