极化不敏感的光学连贯性断层扫描使用伪去极化参考光,以减轻与双折相关的图像工件
Maria Varaka1, Conrad W Merkle1, Lucas May1
1Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna, Austria.
Journal of biomedical optics
|November 6, 2024
概括
在光学连贯断层扫描 (OCT) 图像中的双断层工件会降低图像质量. 这项研究引入了一个简单的去极化器模块,以显著减少这些文物,提高生物医学应用的图像清晰度.
科学领域:
- 生物医学光学 生物医学光学
- 光学工程是指光学工程.
背景情况:
- 光学连贯断层扫描 (OCT) 易受样本或系统双反射引起的图像工件的影响,当使用偏光时.
- 这些文物损害了OCT的图像质量和诊断准确性.
研究的目的:
- 为了减轻OCT图像中双断相关的工件.
- 为了提高图像质量和诊断信息在OCT.
主要方法:
- 在OCT系统的参考臂中,研究了液晶图案延迟剂作为伪去极化剂.
- 使用迈克尔森和马赫-泽恩德干扰仪评估了OCT频谱域中的配置.
- 使用无色四分之一波板测试性能,以控制样本偏振状态.
主要成果:
- 最佳去极化器配置显著减少了3.9dB (米切尔森) 和7.0dB (马赫-泽恩德) 的交叉极化器件.
- 在生物样本 (大黄蜂眼,老鼠尾巴) 中,证明了海上国家和地区信号大小和图像质量的显著改善.
- 实现了与双断层相关的工件的大幅消除,提高了检测到的信号强度.
结论:
- 介绍了一种简单,具有成本效益的技术,以减轻OCT双重突破的工件.
- 该方法可以很容易地在现有的OCT系统中实现.
- 在各种生物医学应用中提高了OCT成像的有效性.
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