射频废除自主运作的甲状腺腺瘤的结果 - 梅奥诊所的经验
Maheswaran Dhanasekaran1, John Schmitz2, Maria Regina Castro1
1Department of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, MN 55905, USA.
Journal of the Endocrine Society
|November 6, 2024
概括
射频切除 (RFA) 有效地治疗自主功能甲状腺结节 (AFTNs),在90.9%的患者中解决甲状腺功能过高症. 与传统治疗相比,这种最少的侵入性选择可以显著减少结节体积,并具有有利的安全性.
科学领域:
- 内分泌学 在内分泌学.
- 最少侵入性手术的方法
- 在瘤学瘤学.
背景情况:
- 自主功能甲状腺结节 (AFTNs) 是甲状腺功能过高的常见原因.
- 目前的治疗方法,如放射性 (RAI) 和手术,存在甲状腺功能低下和其他并发症的风险.
研究的目的:
- 评估射频剥离 (RFA) 作为AFTNs的替代治疗方法.
- 评估RFA在解决甲状腺功能障碍和减少结节体积方面的有效性.
- 为了确定与RFA相关的不良事件对AFTNs.
主要方法:
- 22名单独AFTNs的患者接受了一次RFA会话.
- 监测了患者的治疗结果,以确定甲状腺功能障碍的解决,结节体积的减少和不良事件.
- 随访包括生物化学评估和结节大小测量.
主要成果:
- 甲状腺功能障碍在90.9%的患者中在一次RFA治疗后得到缓解.
- 在3-6个月内,结节体积的平均减少为61.13%.
- 轻微的不良事件包括过渡性高心率和轻度甲状腺功能低下症;没有报告严重并发症.
结论:
- 在治疗AFTNs方面,RFA显示出高效率和良好的安全性.
- RFA为RAI和手术提供了一个可行的替代方案,避免了相关的并发症.
- 考虑在有经验的中心为有毒腺瘤患者提供RFA.
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