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三甘油糖指数与胆结石之间的关联:NHANES 2017-2020年期
Li Gong1, Shujin Fan2,3, Zhenfei Peng1
1Department of Diabetes, Bao'an Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, Shenzhen, China.
Frontiers in endocrinology
|November 6, 2024
概括
甘油三糖 (TyG) 指数与较高的胆结石风险有关. 通过TyG指数显示的胰岛素抵抗的管理可能有助于预防胆结石.
科学领域:
- 代谢综合征是代谢综合征的一种.
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 三甘-葡萄糖 (TyG) 指数与胆结石之间的关系尚不清楚.
- 泰格指数是胰岛素耐药性的可靠指标.
研究的目的:
- 调查TyG指数与胆结石患病率之间的关联.
- 为了确定TyG指数是否可以预测胆结石的形成.
主要方法:
- 分析了2017-2020年国家健康和营养检查调查 (NHANES) 的数据.
- 包括具有TyG指数和胆结石完整数据的参与者.
- 用多变量回归和受限立方线来进行关联分析.
主要成果:
- 在TyG指数和胆结石之间发现了显著的正相关性 (OR = 1.10; 95% CI: 1.01-1.21; p = 0.033).
- 值TyG指数为8.98,表明与此值以下的胆结石存在正相关性 (P < 0.001).
- 亚组分析显示,肥胖个体,女性,年轻个体和血糖水平正常的人群中存在更强的关联.
结论:
- 提升的TyG指数与患上胆结石的可能性增加有关.
- TyG指数作为胆结石风险的潜在生物标志物.
- 针对胰岛素耐药性的干预措施可能会减少胆结石的发生率.
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