急性与慢性精神分裂症中的异常突出:药物治疗和积极的症状是否有所不同?
Bhuvana Prakash Vaidya1, Sonia Shenoy2, Samir Kumar Praharaj2
1Department of Psychiatry, Ramaiah Medical College, Bengaluru, Karnataka, India.
Indian journal of psychiatry
|November 6, 2024
概括
精神分裂症的异常突出性取决于状态,在有症状的患者中显著升高,但在缓解中与对照人群相比较. 药物没有直接影响突出,但可以通过减少积极症状来帮助.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 神经科学是一个神经科学.
背景情况:
- 精神分裂症中异常突出的性质,无论是状态还是特征现象,仍然不清楚.
- 异常突出是精神病的一个关键特征,影响主观经验,并可能导致妄想和幻觉.
研究的目的:
- 评估和比较精神分裂症患者在不同疾病阶段的异常突出.
- 探索异常突出,症状严重程度和精神分裂症中药物使用之间的关联.
主要方法:
- 包括113名受试者:83名精神分裂症患者 (急性症状,慢性药物症状,慢性药物无症状) 和30名健康对照.
- 参与者完成了异常突出的清单 (ASI) 和积极和消极症状的临床评级尺度.
主要成果:
- 在症状精神分裂症组和健康对照组之间发现了异常突出性的显著差异.
- 异常突出与慢性缓解患者的对照人群相似,表明状态依赖.
- 异常突出和积极症状严重程度之间存在强烈的正相关性,不包括负面症状 (SANS).
结论:
- 异常突出性在精神分裂症中升高,具有积极的症状,特别是妄想和幻觉.
- 异常突出似乎取决于状态,在慢性缓解患者中正常化.
- 药物没有直接影响异常突出,但可以通过减轻积极的精神病症状来间接减少它.
相关概念视频
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
63
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
63
Positive Symptoms Schizophrenia: Hallucinations and Delusions
51
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
Hallucinations
Hallucinations in...
51
Psychosis and Antipsychotic Drugs: Overview
183
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
183
Psychosis: Goals of Pharmacotherapy
104
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
104
Negative and Cognitive Symptoms of Schizophrenia
44
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
44
Drug Therapy
39
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
39


