行星健康饮食指数与美国人口中生物衰老之间的关联
Shaoqun Huang1, Haoying Hu2,3, Hongyang Gong4
1Department of Oncology Surgery, Fuzhou Hospital of Traditional Chinese Medicine Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Frontiers in public health
|November 6, 2024
概括
坚持行星健康饮食 (PHD) 与缓慢的生物衰老有关. 这种饮食模式可以通过改善关键健康标志物来帮助预防衰老.
科学领域:
- 营养科学 营养科学
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 星球健康饮食 (PHD) 是2019年EAT-Lancet委员会提出的一种饮食模式.
- 有限的研究已经探索了PHD的抗衰老作用.
研究的目的:
- 通过行星健康饮食指数 (PHDI) 测量PHD的坚持与生物衰老之间的关联.
- 在美国人口中使用多种生物标志物评估生物衰老.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) (1999-2018) 的数据.
- 通过两个24小时的召回评估了饮食摄入量.
- 使用表型年龄,生物年龄,端粒长度和klotho度测量生物衰老.
- 采用加权多变量线性模型,受限立方线和子组分析.
主要成果:
- 较高的PHDI分数与表型年龄 (-0.20岁) 和生物年龄 (-0.54岁) 每增加10个点的降低有关.
- 在PHDI和klotho度之间发现了正相关性.
- 观察到与更高PHDI得分的端粒长度增加.
- 在PHDI和衰老生物标志物之间发现了曲线关系.
结论:
- 坚持PHD与缓慢生物衰老的标志物有显著的相关性.
- 博士学位可能在防止生物衰老方面发挥作用.
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