压力诱导的皮质醇反应预测了对疼痛的同理心:在急性压力期间,胰岛和感觉运动皮层之间的基于任务的连接作用
Zihan Tang1,2, Yadong Liu1,2, Xiaolin Zhao1,2
1Faculty of Psychology, Southwest University, Chongqing, 400715, China.
Neurobiology of stress
|November 6, 2024
概括
急性压力通过改变大脑连接来减少对疼痛的同情心. 对压力的皮质醇反应增加会对同情产生负面影响,这种影响是由参与突出和感觉运动处理的脑网络之间的通信减少所介导的.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 心理生理学 心理生理学
背景情况:
- 对疼痛的同理心对于亲社会行为至关重要.
- 急性心理社会压力可以显著影响同情心.
- 连接压力,同情心和大脑连接的神经机制仍然未被充分探索.
研究的目的:
- 为了研究皮质醇应激反应大小和对疼痛的同理心之间的关系.
- 探索在急性压力期间基于任务的大脑连接在调节同情心中的作用.
- 为了确定神经通路调解压力对同理心的影响.
主要方法:
- 功能磁共振成像 (fMRI) 在急性心理社会压力范式 (ScanSTRESS) 期间.
- 通过唾液样本测量皮质醇应激反应.
- 使用疼痛视频任务评估对疼痛的同理心.
- 分析大脑网络之间的基于任务的功能连接.
主要成果:
- 对疼痛的同理心与皮质醇应激反应的大小呈负相关性 (r = -0.268,p = 0.018).
- 突出和感觉运动网络之间的基于任务的连接与皮质醇反应有负相关性,与同理心有正相关性.
- 胰岛和半中心叶片之间的连接调解了压力诱导的皮质醇对同理心的影响 (间接影响 = -0.0152,p = 0.036).
结论:
- 对疼痛的同理心与压力诱导的皮质醇水平有关.
- 压力引起的大脑连接的变化,特别是突出和感官运动网络之间的变化,影响同情.
- 在压力下,基本和高级大脑区域之间的通信减少是同理心变化的基础.
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