治疗唇癌的治疗意图后的第二次事件:在随访护理的道路上进行导航
Fábio Muradás Girardi1, Amanda de Farias Gabriel2, Vivian Petersen Wagner3
1Department of Head and Neck Surgery, Ana Nery Hospital, Santa Cruz Do Sul, Rio Grande Do Sul, Brazil.
Oral diseases
|November 6, 2024
概括
唇癌幸存者经常发展新的皮肤癌,其中46%的人经历了第二次原发性瘤. 老年患者和上唇基底细胞癌的风险增加. 定期的皮肤检查对于早期检测至关重要.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 癌症研究 癌症研究
背景情况:
- 唇癌治疗的目的是治愈,但随后的事件很常见.
- 了解这些事件对于患者的管理和预后至关重要.
研究的目的:
- 调查治疗唇部癌症治疗后后续事件的发生率,风险因素和结果.
- 为后续协议制定基于证据的建议.
主要方法:
- 在2011年至2021年期间接受治疗的313名唇部癌症患者的回顾性队列研究.
- 对第二次原发性瘤,局部区域复发,结节复发和生存数据的分析.
主要成果:
- 46.32%的患者出现了第二次原发性瘤,主要是皮肤癌 (93%).
- 第二次原发性瘤的1,5年和10年的累积概率分别为32.8%,60.92%和70.92%.
- 老年患者和上唇基细胞癌的风险更高;区域转移影响了生存率.
结论:
- 第二次原发性皮肤瘤是唇癌治疗后最常见的后续事件.
- 年龄和组织学是第二次主要瘤的关键预测因素;标准的皮肤监测至关重要.
- 针对局部发达的唇状细胞癌的具体指导方针应与头癌方案保持一致.
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