皮质脊柱和皮质脊柱突起在中风后的慢性运动行为中具有离散但互补的作用
Myriam Taga1, Yoon N G Hong2, Charalambos C Charalambous1,3
1Department of Neurology, New York University Grossman School of Medicine, New York, New York, United States.
Journal of neurophysiology
|November 6, 2024
概括
在慢性中风幸存者中,皮质脊髓管 (CST) 影响运动控制,而皮质大脑脊髓管 (CReST) 影响肌肉力量. 这两种途径在中风后的上肢功能中发挥互补作用.
科学领域:
- 神经科学是一个神经科学.
- 运动康复 运动康复
- 脑中风恢复 脑中风恢复
背景情况:
- 脑卒中经常导致上肢运动缺陷,影响力量,控制和肌肉个性化.
- 脊髓前皮层 (CST) 和脊髓前皮层 (CReST) 在中风后的臂功能中的作用尚未完全理解.
研究的目的:
- 为了研究异位CST和逆位CReST投射强度和形手臂和手中的慢性运动行为之间的差异关系.
- 为了确定运动缺陷的严重程度是否在近端 (手臂) 和远端 (手) 之间有所不同.
主要方法:
- 一项涉及14名慢性中风患者和27名健康对照者的横截面研究.
- 跨磁刺激 (TMS) 用于测量CST和CReST投射强度在两和第一个背部骨肌中.
- 定量运动测试评估了力量,运动控制和肌肉个性化.
主要成果:
- 与健康对照组相比,中风患者的运动控制和肌肉个性化表现较差,尽管肌肉强度相似.
- 较强的ipsilesional CST投影与两个肌肉中的更好的运动控制相关.
- 较强的逆伤性CReST投影与两个肌肉的更好的肌肉力量相关;更强的CST投影与更好的双肩个体化有独特的关系.
结论:
- 垂体CST和垂体CReST在介导手和手的运动行为方面表现出专门的,但互补的作用.
- 运动控制和肌肉个性化的缺陷没有细分偏差,突出显示了这些下降运动通路的功能范围.
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