结合基于生物学和MRI数据的建模,预测三阴性乳腺癌患者对新辅助化疗的反应

Casey E Stowers1, Chengyue Wu1, Zhan Xu1

  • 1From the Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, Tex (C.E.S., C.W., J.I.T., T.E.Y.); Chandra Family Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, Tex (S.K., J.I.T.); Livestrong Cancer Institutes, The University of Texas at Austin, Austin, Tex (T.E.Y.); Departments of Imaging Physics (C.W., Z.X., J.B.S., J.M., T.E.Y.), Abdominal Imaging (G.M.R.), Breast Imaging (C.W., G.M.R.), Breast Medical Oncology (C.Y.), Biostatistics (C.W.), and Institute for Data Science in Oncology (C.W.), The University of Texas MD Anderson Cancer Center, Houston, Tex; and Departments of Biomedical Engineering (C.W., T.E.Y.), Diagnostic Medicine (J.I.T., T.E.Y.), and Oncology (T.E.Y.), The University of Texas at Austin, 107 W Dean Keeton St, Stop C0800, Austin, TX 78712.

PubMed
概括

这项研究结合了深度学习和基于生物学的模型,利用MRI数据预测乳腺癌对新辅助化疗 (NAC) 的三重阴性反应. 综合模型准确地预测了瘤变化,在治疗开始之前帮助治疗决策.

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