利益相关者对心力衰竭的看法 减少喷射分数多药丸:多中心混合方法研究
Justin C Chen1, Colette DeJong1,2, Mansi Agarwal1
1Department of Medicine, Division of Cardiology, Washington University in St. Louis School of Medicine, St. Louis, MO (J.C.C., M.A., M.D.H., A.A.).
Circulation. Cardiovascular quality and outcomes
|November 6, 2024
概括
对心力衰竭和减少喷射率 (HFrEF) 的多药丸是非常可接受的,适当的和可行的. 患者和提供者对HFrEF多药剂的优先考虑,设计,成本和公平性将指导未来的试验.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 结合所有指导方针指导的治疗心力衰竭与减少喷射率 (HFrEF) 的多药丸,可以改变治疗.
- 这种多药药策略的可接受性,适当性和可行性仍未确定.
研究的目的:
- 确定患者和提供者设计HFrEF多种药物的优先事项.
- 评估基于多种药丸的策略对心力衰竭护理的潜在影响.
主要方法:
- 从4月到2023年12月进行了一项融合平行混合方法研究.
- 医生调查 (n=214) 评估了HFrEF多种药物的可接受性,可行性和适当性.
- 与患者 (n=9) 和提供者 (n=22) 的深入访谈探索了护理,多药剂设计和支持策略.
主要成果:
- 医生评价HFrEF多种药物高度可接受 (4.2/5),适当 (4.1/5),可行 (4.1/5).
- 关键主题包括HFrEF护理的决定因素,多药剂设计的供应商偏好,成本和公平问题以及研究优先事项.
- 患者和医疗服务提供者采访强调了需要定位性和考虑健康公平的需要.
结论:
- 对HFrEF的基于多种药丸的策略被认为是高度可接受的,适当的和可行的.
- 在多药片设计,可定位性和健康公平性方面确定优先事项将为未来的临床试验和实施策略提供信息.
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