正常体重 中心肥胖及其对2型糖尿病的影响
Jing Bai1, Yifan Zhang1, Li He2
1College of Physical Education and Sports, Beijing Normal University, Beijing, 100875, China.
Current diabetes reports
|November 6, 2024
概括
正常体重肥胖 (NWO) 和正常体重中心肥胖 (NWCO) 分别影响16.1%和21.1%的成年人. 这些情况与患2型糖尿病的风险更高有关,特别是在女性和非亚洲人中.
科学领域:
- 代谢健康 代谢健康
- 肥胖问题研究研究
- 糖尿病流行病学 糖尿病流行病学
背景情况:
- 正常体重肥胖症 (NWO) 和正常体重中心肥胖症 (NWCO) 代表了与传统肥胖症不同的代谢表型.
- 了解NWO和NWCO对健康的影响对于公共卫生和临床实践至关重要.
研究的目的:
- 提供关于NWO和NWCO对成年人2型糖尿病的影响的最新文献综述.
- 综合有关NWO/NWCO与2型糖尿病的流行和关联的现有证据.
主要方法:
- 14项研究的系统综述和元分析 (9个横截面,5个队列) 涉及334438名受试者.
- 汇总的流行率和赔率比率被计算出来,以评估NWO,NWCO,以及它们与2型糖尿病的关联.
- 根据性别,地区和定义方法进行了子组分析.
主要成果:
- NWO的综合流行率为16.1%,NWCO为21.1%,女性和非亚洲人群的流行率更高.
- 2型糖尿病与NWO和NWCO显著相关 (合并OR:1.82).
- 在各种子组中观察到一致的关联,表明NWO/NWCO和2型糖尿病之间存在强有力的联系.
结论:
- NWO和NWCO是普遍存在的疾病,特别是在特定的人口群体中.
- 在NWO/NWCO和2型糖尿病风险增加之间存在显著和一致的关联.
- 研究结果强调需要有针对性的干预措施和公共卫生战略来应对这些代谢风险.
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