身体圆指数与慢性脏病的关联:NHANES 1999-2018年基于人口的横截面研究
Hongliang Cao1, Chengdong Shi1, Zulipikaer Aihemaiti2
1Department of Urology, The First Hospital of Jilin University, Changchun, 130021, China.
International urology and nephrology
|November 6, 2024
概括
高体圆度指数 (BRI) 是慢性病 (CKD) 的危险因素. 这项研究表明,BRI可能成为CKD预防和治疗策略的新指标.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
- 肥胖问题研究研究
背景情况:
- 肥胖与慢性病 (CKD) 有关.
- 通过身体圆度指数 (BRI) 测量的身体脂肪分布与CKD风险之间的关系仍然不清楚.
研究的目的:
- 调查BRI与患CKD的风险之间的关联.
- 探索BRI作为CKD风险评估的潜在指标.
主要方法:
- 分析了1999-2018年国家健康和营养检查调查 (NHANES) 的41,953名参与者的数据.
- 利用多变量逻辑回归,子组分析和平滑曲线拟合来检查BRI-CKD关系.
主要成果:
- 较高的BRI水平 (四分位数4) 与CKD风险增加显著相关 (OR = 1.30).
- BRI和CKD风险之间的正相关性在各种子组中是一致的.
- 在BRI和CKD风险之间观察到大致线性正相关性.
结论:
- BRI与CKD风险的相关性大致是线性的.
- 在CKD患者中,BRI可能代表了一种提高预防和治疗策略的新指标.
- 需要进一步的研究来充分阐明这种关联.
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