在孤立的严重的二次三腹吐中HFpEF的患病率
Jwan A Naser1, Tomonari Harada1, Yogesh N Reddy1
1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
JAMA cardiology
|November 6, 2024
概括
在患有严重的二次三腹吐 (STR) 的患者中,常常低诊断保存喷射分数 (HFpEF) 的心力衰竭. 左心房功能评估显示,对这些患者诊断HFpEF有希望.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 心脏成像 - - 心脏成像
背景情况:
- 二次三回 (STR) 是各种心脏和肺部疾病中常见的发现.
- 保持喷射分数 (HFpEF) 的心力衰竭和毛囊前肺高血压 (PH) 是 STR 的潜在潜在原因,可能会被忽视.
- 识别这些疾病对于适当的患者管理至关重要.
研究的目的:
- 为了确定HFpEF和毛囊前PH在患有严重孤立STR的患者中的患病率.
- 评估非侵入性方法在确定该患者群体中HFpEF的有效性.
主要方法:
- 对54名患有严重孤立性STR的成人患者进行了回顾性横截面研究,这些患者接受了运动右心导管注射 (RHC).
- 基于RHC衍生的肺动脉压标准对HFpEF进行诊断.
- 使用标准心声学参数评估腹功能障碍 (DD).
- 对HFpEF歧视的左心房空化分数和应变的评估.
主要成果:
- 在74%的患者中发现了HFpEF,但在RHC之前只有35%的患者被诊断出HFpEF.
- 在没有HFpEF的剩余患者中,71%的患者被诊断出了前毛细管PH.
- 在60%的患者中,没有标准的DD标准,后来被诊断为HFpEF.
- 左心房排空分数和应变在识别HFpEF时表现出高准确性.
结论:
- 在患有严重孤立STR的患者中,HFpEF的诊断往往不足.
- 在这个群体中,毛囊前PH也很常见.
- 目前的休息DD标准不足以诊断这些患者的HFpEF.
- 左心房功能评估是HFpEF诊断严重孤立STR的有希望的非侵入性工具.
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