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Updated: Jun 8, 2025

Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains
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定义的具有细胞内在透性的α-螺旋小蛋白的设计和表征

Xin-Chun Chen1, Xiang-Wei Kong2, Pin Chen3

  • 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou 510060, P. R. China.

Computational biology and chemistry
|November 6, 2024
PubMed
概括

研究人员开发了一种新的设计原则,用于细胞透的微型蛋白质,提高药物输送. 一个带有正电荷的新型螺旋结构显著改善了细胞透,超过了现有的方法.

关键词:
细胞的透性 细胞的透性细胞内存症 (Endocytosis) 是一种细胞内存症.螺旋状蛋白质是一种螺旋状蛋白质.高通量选的高通量选蛋白质 de novo 设计

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