追踪和测试食品流行病学上与婚礼招待会上的诺罗病毒爆发有关
Efstathia Papafragkou1, Amanda Kita-Yarbro2, Zihui Yang1
1Food and Drug Administration, Laurel, Maryland, United States.
Journal of food protection
|November 6, 2024
概括
威斯康星州的一场婚礼爆发与水果沙拉有关,证实了诺罗病毒的污染. 这项调查结合了采访,实验室测试和食品分析,以确定疫情的爆发.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 食物传播疾病 食物传播疾病
背景情况:
- 诺罗病毒疫情带来了重大的公共卫生挑战,通常与受污染的食物有关.
- 调查食物传播疾病的爆发需要多学科的方法.
研究的目的:
- 在婚礼招待会上确定疑似诺罗病毒爆发的来源和致病剂.
- 确认特定食品与诺罗病毒传播之间的联系.
主要方法:
- 进行了一项回顾性队列研究,采访了56名与会者.
- 利用实时逆转录聚合酶链反应 (RT-qPCR) 进行诺罗病毒检测.
- 进行了用于诺罗病毒基因类型和遗传学分析的桑格测序.
主要成果:
- 鉴定出水果沙拉是感染的可能载体 (风险比率3.2).
- 在参加者便样本和剩余的水果沙拉中检测到诺罗病毒 (GII.4悉尼).
- 在临床和食品样本之间确认了98%的核酸相似性.
结论:
- 果沙拉被证实是诺罗病毒爆发的来源.
- 综合的流行病学,病毒学和环境数据有效追踪了污染.
- 强调食品安全对于预防大规模疫情的重要性.
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