相关实验视频
Updated: Jun 8, 2025
07:22
Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
8.1K
超过5:1的蜜蜂/黄蜂毒-特定IgE比率表明双重敏感患者的罪祸首是昆虫
Simon Tischler1, Axel Trautmann1, Matthias Goebeler1
1Department of Dermatology, Venereology, and Allergology, University Hospital Würzburg, Würzburg, Germany.
The journal of allergy and clinical immunology. In practice
|November 6, 2024
概括
特定IgE水平的5:1比率有助于在双重敏感患者中识别主要的毒素过敏原. 这一发现可以指导诊断,并避免不必要的双重免疫治疗蜜蜂毒 (BV) 和黄蜂毒 (VV) 的过敏.
科学领域:
- 过敏原免疫疗法免疫疗法
- 临床免疫学 临床免疫学
- 诊断性过敏测试是对过敏的测试.
背景情况:
- 许多对昆虫毒素过敏的患者对蜜蜂毒 (BV) 和黄蜂毒 (VV) 都敏感.
- 区分真正的双重过敏与交叉反应性对于有效治疗至关重要.
- 真正的双毒过敏是相对罕见的.
研究的目的:
- 确定比较特定的IgE水平是否可以在双重敏感患者中识别主要的毒素过敏原.
- 评估是否组件解决诊断是必要的双重免疫疗法决策.
主要方法:
- 对1069名患者进行了回顾性分析,并进行了全面的过敏学检查.
- 对BV,VV,rApi m 1 和rVes v 5进行定量特定IgE测试.
- 在双重敏感患者中分析了BV/VV特异性IgE比率.
主要成果:
- 在52.1%的双重敏感患者中,对BV或VV的特定IgE水平的5:1或更大的优势被观察到.
- 在97.1%的病例中,占主导地位的IgE水平正确地预测了对该特定毒素的单一过敏.
- 当存在明显的IgE优势时,组件解决的诊断并不总是必要的.
结论:
- 5:1的特定IgE比率有效地识别了双重敏感患者的罪祸首毒素.
- 组件解决的诊断可以保留在IgE比率低于5:1的情况下.
- 对特定成分 (如rApi m 1和rVes v 5) 的敏感性本身并不需要双毒药免疫疗法.
关键词:
过敏测试是对过敏的测试.艾比姆是一只.没有症状的无症状.组件 组件 组件 组件 组件双重过敏是一种双重过敏.双重敏感化 双重敏感化黄斑类动物 (Hymenoptera) 是一个类动物.在 IgE 中,IgE 是昆虫的毒液是一种昆虫的毒.在5月5日晚上.更多相关视频
07:10Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
Published on: April 21, 2019
16.3K
06:34A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
10.0K
相关概念视频
02:06Allergic Reactions
27.2K
Overview
27.2K
00:42Cross-reactivity
31.0K
Overview
31.0K
01:10Antibody Structure
59.2K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
59.2K
01:30Hypersensitivities
524
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
524