大脑血流和动脉过渡时间对老年人运动训练的反应
Jack Feron1, Foyzul Rahman2, Sindre H Fosstveit3
1School of Sport, Exercise and Rehabilitation Sciences, University Birmingham, Birmingham, UK; Centre for Human Brain Health, University Birmingham, Birmingham, UK.
NeuroImage
|November 6, 2024
概括
老年人的运动训练可能会降低大脑中的脑血流 (CBF),特别是在显著的健身增长的情况下. 这种变化并没有影响研究组的认知功能.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 运动生理学 运动生理学
背景情况:
- 大脑血管健康随着年龄的增长而下降,其特点是大脑血流 (CBF) 减少和动脉传输时间 (ATT) 增加.
- 运动干预措施显示出改善老年人大脑健康的潜力,但它们对CBF和ATT的具体影响尚不清楚.
研究的目的:
- 为了研究26周的运动干预对休息灰质大脑血流 (CBFGM) 和动脉过渡时间 (ATTGM) 在健康的老年人的影响.
- 为了确定CBFGM或ATTGM的变化是否与干预后认知功能的改变有关.
主要方法:
- 进行了一项随机对照试验,涉及65名健康的老年人 (60-81岁),参与者被分配到运动组 (n=32) 或对照组 (n=33).
- 多次延迟伪连续性动脉旋转标签被用于测量26周干预前后的全球和区域CBFGM和ATTGM.
- 通过峰值氧气消耗 (V̇O2峰) 来评估心肺健康.
主要成果:
- 在干预后,在运动和对照组之间没有观察到总体CBFGM或ATTGM的显著差异.
- 一部分运动参与者实现了显著的心肺健康增长 (∆V̇O2峰>>2毫升/千克/分钟) 显示全球CBFGM的减少.
- 认知功能在两组中保持不变,CBFGM/ATTGM和认知表现的变化之间没有发现相关性.
结论:
- 老年人的运动训练,特别是当导致显著的心肺健康改善时,可能与全球CBFGM的减少有关.
- 这些运动诱导的CBFGM变化似乎不会对健康老年人的认知功能产生负面影响.
- 需要进一步的研究来探索与运动相关的CBFGM改变在老化大脑中的机制和长期影响.
相关概念视频
Exercise and Cardiovascular Response
740
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
740
Exercise and Cardiac Output
929
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
929


