节点-RADS:对诊断绩效的系统审查和元分析,恶性瘤率的分类,以及观察者之间的可靠性
Jingyu Zhong1, Shiqi Mao2, Haoda Chen3
1Department of Imaging, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China.
European radiology
|November 6, 2024
概括
节点报告和数据系统1.0 (Node-RADS) 显示了对淋巴结癌评估的强大诊断性能,恶性瘤的概率按类别增加. 然而,关于观察者间可靠性的证据不足可能会限制其临床使用.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 诊断的准确性 诊断的准确性
背景情况:
- 结构化的报告系统对于一致的淋巴结评估至关重要.
- 节点报告和数据系统1.0 (Node-RADS) 旨在标准化对淋巴结癌的评估.
- 关于Node-RADS诊断性能和可靠性的证据需要进行全面的总结.
研究的目的:
- 系统地审查和元分析Node-RADS.的诊断性能.
- 为了估计Node-RADS.的恶性瘤率,按类别计算.
- 评估CT和MRI淋巴结评估中Node-RADS的观察者间可靠性.
主要方法:
- 对五个电子数据库进行系统搜索 (2021年1月至2024年4月).
- 包括对Node-RADS进行淋巴结癌症评估的初级研究.
- 使用QUADAS-2和QAREL工具进行质量评估;用双变量随机效应模型估计诊断准确性.
主要成果:
- 包括6个Node-RADS-CT和3个Node-RADS-MRI研究,涵盖9种癌症类型.
- 节点-RADS ≥3 的曲线下的面积 (AUC) 为 0.92,节点-RADS ≥4 的曲线下的面积为 0.91.
- 对于Node-RADS类别1-5的恶性瘤比率在4%至100%之间;观察者之间的可靠性是相当大的.
结论:
- 节点-RADS表现出有前途的诊断性能,在不同类别中增加恶性瘤的概率.
- 该系统显示了高的诊断准确性 (AUC 0.92) 和每个类别的清晰恶性瘤率.
- 关于观察者间可靠性的证据不足可能会阻碍Node-RADS.的广泛临床实施.
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