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Updated: Jun 8, 2025

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
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Published on: June 19, 2019

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氨酸和PKA之间的 postsynaptic竞争调节了哺乳动物的睡眠和清醒周期

Yimeng Wang1, Siyu Cao1, Daisuke Tone1,2

  • 1Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

Nature
|November 7, 2024
PubMed
概括

蛋白质激酶A (PKA) 促进清醒,而蛋白质酸酶PP1和氨酸通过调节突触蛋白质酸化来促进睡眠. 这些在激发后突触的对立作用控制睡眠时间.

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