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Updated: Jun 8, 2025

Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells
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Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells

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通过心脏,血液和瘤检查点心肌炎的免疫反应

Steven M Blum1,2,3,4,5, Daniel A Zlotoff1,3,4,5,6, Neal P Smith1,3,5

  • 1Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.

Nature
|November 7, 2024
PubMed
概括

免疫检查点抑制剂可能导致心肌炎. 这项研究揭示了患者心脏和血液中的免疫细胞变化,没有发现直接的心脏自身抗原识别,但确定了致命结果的生物标志物.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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