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Updated: Jun 27, 2026

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    全基性造血干细胞移植 (allo-HSCT) 改善了FLT3-ITD阳性急性髓性白血病 (AML) 的年轻成年人的结局. 与化疗相结合的sorafenib与单独的化疗相比没有显著的差异.

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    Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

    Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...