在年轻海军陆战队员中对SARS-CoV-2连续病变的临床和功能评估 - 一项小组研究
Chad K Porter1, Charmagne G Beckett1, Elizabeth Cooper1
1Naval Medical Research Command, Silver Spring, MD, USA.
Lancet regional health. Americas
|November 7, 2024
概括
四分之一的年轻,健康的美国海军陆战队员经历了长期的COVID症状,包括嗅觉丧失,呼吸短促和疲劳,长期影响身体健康和心理健康.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在SARS-CoV-2感染后的长期不良健康结果是一个重大问题,特别是对于年轻人来说.
- 在健康的年轻成年人群中评估这些结果对于了解长期发病率至关重要.
- 美国海军陆战队代表了一个独特的队列,研究COVID-19的长期影响,因为他们的健康状况和标准化的健身评估.
研究的目的:
- 评估和描述SARS-CoV-2感染后美国海军陆战队队伍的长期不良健康结果.
- 为了确定这一群体中COVID-19 (PASC) 后急性后果的流行率和类型.
- 评估PASC对身体健康和心理健康的影响.
主要方法:
- 一个纵向的,前性的观察研究设计被采用,利用美国海军陆战队的队列.
- 在症状出现至少4周后,使用问卷和验证的健康指标质量来评估COVID-19 (PASC) 后急性后果.
- 使用标准化美国海军陆战队健身测试指标评估身体健康,并与疫情前队列进行比较.
主要成果:
- 在798名感染SARS-CoV-2的海军陆战队员中,197名 (24.7%) 患有PASC.
- 最常见的PASC症状包括味觉/嗅觉丧失 (41.6%),呼吸短促 (37.6%) 和咳 (22.8%).
- 与对照人群相比,患有PASC的参与者表现出更高的体质,抑郁和焦虑症状,并表现出身体健康状况下降,包括运行时间更慢.
结论:
- 大约四分之一的健康的年轻成年美国海军陆战队员在感染SARS-CoV-2后经历了长期的身体,认知或精神疾病后果.
- 海军陆战队的PASC与功能性表现和身体健康的长期下降有关.
- 感染SARS-CoV-2可能会对相当一部分年轻成年人的健康和功能能力产生负面影响.
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