在Fontan患者的肝脏成像:超声波如何与截面成像相比?
Maria L Garagiola1, Stephanie Bm Tan1,2, Rafael Alonso-Gonzalez1
1Toronto ACHD Program, Division of Cardiology, University of Toronto, Toronto, Ontario, Canada.
超声波有效地选Fontan患者的肝硬化,尽管它在特异性上有局限性. 在这项研究中,诊断出肝硬化和死亡率或移植之间没有联系.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 医疗成像医学成像
背景情况:
- 喷泉循环患者容易患肝硬化.
- 对于Fontan患者肝硬化超声波的诊断准确性和临床影响尚不清楚.
研究的目的:
- 评估超声波 (US) 的诊断性能,以检测患有Fontan循环的成年人肝硬化 (LC).
- 确定诊断的LC与死亡率或移植之间的相关性.
主要方法:
- 这是一项回顾性研究,分析了来自131名成年Fontan患者的数据.
- 肝脏美国发现与横截面成像 (CT/MRI) 的比较.
- 评估诊断准确性,kappa一致性,并使用考克斯回归来评估结果.
主要成果:
- 超声波显示出对肝硬化特征的高灵敏度,但与横截面成像相比,特异性较低.
- 78%的美国人被诊断出肝硬化,而90%的人通过截面成像 (kappa=0.21) 来诊断出肝硬化.
- 在肝脏辅酶体变化/肝硬化和死亡率/移植之间没有发现显著的相关性.
结论:
- 肝脏超声波对于成年Fontan患者查和监测肝硬化特征非常有价值.
- 单变量分析表明肝硬化与死亡率或移植等不良结果之间没有关联.
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