巨细胞动脉炎中的第六头骨神经麻:系统性审查
Haruki Sawada1, Yoshito Nishimura1,2, Hiromichi Tamaki3
1Department of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, USA.
Archives of rheumatology
|November 7, 2024
概括
巨细胞动脉炎 (GCA) 可以导致第六头骨神经麻,导致双眼视. 及时的皮质类固醇治疗往往可以缓解症状,但对这种潜在并发症的认识对于及时诊断和管理至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 类风湿病学 类风湿病学
背景情况:
- 巨细胞动脉炎 (GCA) 是一种全身性血管炎,可以影响神经.
- 孤立的第六头骨神经麻 (abducens神经麻) 可能是GCA的呈现征兆,有时伴有微妙的眼睛.
研究的目的:
- 在GCA患者中审查和描述孤立的第六头骨神经麻.
- 提高对这种可能被忽视的GCA.表现的理解.
主要方法:
- 在PRISMA扩展范围审查后进行系统性审查.
- 在 MEDLINE 和 EMBASE 搜索了关于"头骨神经六","神经"和"巨细胞动脉炎"的文章,截至 2022 年 12 月 22 日.
主要成果:
- 包括25篇文章 (7篇观察性研究,18篇案例报告).
- 第六神经麻占高达48%的双眼视在GCA.
- 88.2%的患者经历了皮质类固醇的症状缓解;中位数缓解时间为24.5天.
结论:
- 第六神经是一种显著的,虽然有时是微妙的,GCA的表现.
- 大多数病例通过皮质类固醇治疗得到缓解,但可能发生持续性眼.
- 在GCA中增加对第六神经麻的临床意识对于及时诊断和治疗至关重要.
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